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Estudio revela que la mayoría de las funciones génicas humanas son ancestrales y ofrece el compendio más completo sobre genes codificantes.

Publican el compendio más exhaustivo de las funciones del genoma humano

17 de marzo de 2025

Un reciente estudio ofrece el compendio más completo sobre las funciones de los genes humanos, cubriendo el 82 % de los genes codificantes. Usando un enfoque evolutivo, reveló que la mayoría de las funciones génicas son ancestrales, con pocas nuevas funciones desde la aparición de los mamíferos con placenta. La plataforma PAN-GO fue clave en el análisis. De acuerdo con el autor, el estudio refuerza el papel de la ciencia española en la investigación biomédica global.

El artículo fuente, de libre acceso, se encuentra publicado en la revista Nature: A compendium of human gene functions derived from evolutionary modelling