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Anclaje de citocinas en micropartículas potencia respuesta inmune contra el cáncer.

Desarrollan una forma de estimular las células inmunitarias para combatir el cáncer

19 de abril de 2024

Un estudio reciente revela un nuevo enfoque para activar y estimular las células inmunitarias contra el cáncer. Los investigadores han desarrollado un método que utiliza proteínas citocinas, pero con la innovación de anclarlas a micropartículas que se concentran en el tumor, reduciendo así el riesgo de efectos secundarios y maximizando la respuesta inmune contra las células cancerosas. Con ello, el equipo de expertos, liderados por Rong Tong y Wenjun Cai, han conseguido activar las células inmunes del cuerpo y reprogramarlas para atacar y destruir las células cancerosas de una manera más efectiva.

El artículo fuente, de libre acceso, fue publicado en la revista Science Advances: Noncovalently particle-anchored cytokines with prolonged tumor retention safely elicit potent antitumor immunity